Organisme : Instituts de recherche en santé du Canada

  Projets financés à l'Université Laval
    A comprehensive genotype-phenotype map of a eukaryotic complexome
    Adult Health Outcomes in Male and Female Victims of School Bullying: A Longitudinal and Genetically Informed Study of Underlying Bio-Physiological Mechanisms
    Age- and sex-specific contribution of nuclear or membrane progesterone receptors on respiratory control in mice.
    Age of Blood in Children in Pediatric Intensive Care Units (ABC-PICU): a multicenter international pragmatic double blind randomized clinical ...
    Analysis of T cell reservoirs in visceral tissues of pathogenic and non-pathogenic primate models of lentiviral SIV infection
    An autologous cell therapy approach to treat Duchenne muscular dystrophy using engineered muscle tissue derived from induced pluripotent stem cells
    Androgen receptor activation by glucocorticoid metabolite : a novel player in the physiopathology of respiratory distress syndrome in neonates
    An integrated self-referral el_heath strategy for improving rapid and direct access to youth mental health services: A stepped-wedge, cluster randomized controles trial in six canadian health care selfings
    An international multi-center prospective, inception cohort study of neuropsychiatric systemic lupus erythematosus (NPSLE)
    A Pilot Randomized-Controlled Trial of Lipoprotein(a) Lowering for the Prevention of Aortic Valve Disease - Translating genomic knowledge for cardiovascular prevention
    A pragmatic randomized controlled trial of group transdiagnostic cognitive-behaviour therapy for anxiety disorders in primary care
    A randomized trial of enteral glutamine to minimize thermal injury (the RE-ENERGIZE Study)
    Beta arrestin mediated dopamine signaling for psychiatric drugs discovery.
    Biological embedding of childhood adversity and its long-lasting impact on mental health: A longitudinal study of a population-based sample adolescents
    Canadian Atrial Fibrillation Stroke Prevention Intervention Network (CAF-SPIN)
    Cellular and molecular mechanisms regulating dopmaminergic circuit formation.
    Characterisation and roles of isoprostanes in the pathophysiology of preeclampsia.
    Clinical and molecular heterogeneity of Paget's disease of bone.
    Clinical application of a novel molecule that expands human cord blood stem cells
    Comprendre le rôle des cellules immunitaires dans le psoriasis grâce au génie tissulaire
    Connecting the Cell-Type Specific Chromosome Architecture to Gene Regulation, Development and Diseases
    Contribution of the orphan receptor NR4A1 in the control of influenza virus infection and lung inflammation.
    Corneal transplantation: The traditional paradigm revisited
    Correction of the dystrophin gene with Zinc Finger Proteins and TAL effector nuclease
    Corticothalamic oscillations during sleep and waking behavioral states, from sleep-dependent plasticity to memory consolidation.
    Defective prostaglandin biosynthesis pathways and abnormal crosstalk at the endometrial/peritoneal interface: role in the pathophysiology of endometriosis.
    Depression 2 to 4 years after traumatic brain injury: a longitudinal study of psychosocial predictors, impacts, and barriers to access mental health resources.
    Des institutions et des femmes: Evolution du nursing psychiatrique au Québec, 1912-1974
    Detailed functional study of Argonaute proteins in microRNA-mediated gene regulation.
    Development and validation of Canadian health literacy measurement tool for chronic desease management
    Development of a safe, effective and clinically acceptable VSV-based HIV vaccine
    Développement et utilisation de biomarqueurs permettant l'évaluation de l'exposition solaire accumulée par les yeux humains.
    Diagnosis, prognosis and classification of retinopathies : Comparing time-amplitude (TAD) with time-frequency domain (TFD) analyses of the electroretinogram
    Dopamine and Risk for Addictions
    Drug resistance mechanisms in the human pathogen Leishmania
    ED Ultrasonographic Regional Anesthesia to prevent Incident Delirium in Hip Fracture Patients (EDU_RAPID)
    Effect of free sugar replacement with non-nutritive sweeteners (NNS) on metabolic health of high sugar sweetened beverages (SSB) consumers: potential role of the gut microbiome
    Effect of pain on the motor system: Neural mechanisms and implications for rehabilitation
    Effect of the gut microbiota and their generated metabolites on HIV-1 biology in CD4+ T cells.
    Elucidating the role of alpha2beta1 integrin in the chemoresistance of acute lymphoblastic leukemia.
    End-of-life ethical deliberations : Characterization of interprofessional clinical practices.
    Environmental Contaminants and Adolescent Development.
    Examen de profils chez les patientes présentant une anorexie mentale et réponses aux interventions : études multicentrique.
    Exploring the functions of the Bub1 and BubR1 kinases during mitosis.
    Exploring the role of phosphoinositides in the trafficking of proteins to the apical complex in the malaria parasite Plasmodium falciparum.
    Exposition cumulée aux stresseurs psychosociaux, marqueurs inflammatoires, télomères et fonction cognitive : une étude prospective de 20 ans
    Expression profiling in antibiotic resistant Streptococcus pneumoniae
    First-trimester prediction of preeclampsia and other placenta-mediated pregnancy complications
    (FRQS 70782) Biological markers of altered emotional regulation in chronic insomnia and their relationship with treatment responses to cognitive behavioural therapy
    Functional dissection of the microRNA pathway.
    Functions of poly(ADP-ribose) polymerases in DNA double-strand break processing and pathway choice.
    Genetic dissection of conserved cross talks among pathways involved in human diseases in a model system
    Genetic imprinting in calcific aortic valve disease: role of H19.
    Genetics and functional genomics to dissect the molecular basis of bicuspid aortic valves.
    Glia-neuron crosstalk in early amyotrophic lateral sclerosis pathogenesis.
    HIV-1 reservoir in the CNS: mode of establishment and consequences of purging strategies on this reservoir.
    Immunosuppressive function of S100A8 in arthritis.
    Impaired systemic angiogenesis in pulmonary arterial hypertension.
    Implementing shared decision making in interprofessional home care teams.
    Implication of atherosclerotic pathways and metabolic risk factors in the structural deterioration of bioprosthetic heart valves-II
    Implication of DEPTOR in the regulation of glucose/lipid homeostasis
    Importance of tissue-resident memory (Trm) CD8 T cells in controlling SIV infection in mucosal sites of viral entry.
    Inégalités sociales de santé mentale, contraintes psychosociales au travail, vie active et retraite: une étude prospective de 20 ans.
    Inégalités sociales, environnement psychosocial au travail, vie active, retraite et santé cardiovasculaire: une étude prospective de 20 ans chez 9000 femmes et hommes.
    Inhibitory control of hippocampal inhibitory circuits: cellular mechanisms and function
    Integration of human herpesvirus type 6 into chromosomes: Mechanisms and consequences.
    Interactions between astrocytoma cells and blood vessels.
    Interplay between homologous recombination and anti-recombination activities at broken DNA replication forks and genomic instability.
    Investigating electroretinography(ERG) as a new method for predicting conversion to psychosis in youth at clinical high risk.
    In vivo genome editing as a novel class of human therapeutics to treat pediatric metabolic disorders.
    Long-term immunogenicity and clinical efficacy of the quadrivalent HPV vaccine in HIV positive girls and women
    Maternal Omega-3 supplementation to reduce Bronchopulmonary Dysplasia in very Preterm Infants : A Randomized controlled trial (MOBYDIck trial).
    Mechanisms of antiviral drug resistance for Herpesviruses.
    Mechanisms of Aspergillus induced chronic airway disease
    Mechanisms of dendritic integration and plasticity in GABAergic inhibitory interneurons
    Mechanisms of therapeutic efficacy of deep brain stimulation in Parkinson's disease
    MicroRNA-15 dysregulation in sporadic Alzheimer's disease : testing the "multiple hit" hypothesis in neurodegenerative disorders
    Modulation of cell metabolism : Role of UDP-glucuronosyltransferase (UGT1A) proteins
    Molecular mechanism-based study for the sex-specific susceptibility in blood cancer.
    Molecular mechanisms orchestrating epithelial cell polarity.
    Motor control: Brainstem control of locomotion
    Mutant protein spread in Huntington's disease and its implications for other neurodegenerative disorders of the CNS.
    Neonatal stress and the neuroendocrine basis for sex-specific panic-related respiratory disorder in rat.
    Neuronal mechanisms of stress-induced overeating.
    Neuroprotection and immunomodulation in the enteric nervous system for the treatment of Parkinson's disease
    Neurosciences and the Afterlife of Death: Re-imagining Notions of Suicide Risk.
    New roads taken to identify and study the biological significance of host-derived molecules incorporated in HIV-1.
    Omega current underlies SCN5A mutations associated with complex cardiac arrhythmias and dilated cardiomyopathy.
    One carbon metabolism in the human parasite Leishmania.
    Optimizing physician training in motivational communication (MC) skills for health behavior change
    Penetrating wound induced epileptogenesis.
    Pharmacogenomics of human UDP-glucuronosyltransferases: From single genetic polymorphisms to a complex regulation of enzyme function
    Phase I/II clinical trial of myoblast transplantation to Duchenne Muscular Dystrophy patients.
    Plasticity of inhibition in spinal sensory pathways.
    Possible outcomes of Leishmania co-infection on HIV-1 immunopathogenesis, latency and reactivation.
    Possible outcomes of Leishmania co-infection on HIV-1 immunopathogenesis, latency and reactivation.
    Postprandial energy metabolism of brown fat in humans
    Prevention and control of chronic and respiratory viral diseases using PapMV nanoparticles.
    Probing for sphingosine-1 phosphate signalling in asthma
    Processus d'aide à la décision, gestion du risque obstétrical et du mode d'accouchement après césarienne au Québec (PRISMA).
    Projet pilote d'Équipes de Soins Primaires intégrées (ESPI) au Québec : évaluation d'implantation et d'effets
    Pronostic biopsychosocial des douleurs thoraciques inexpliquées suite à une consultation dans une unité d'urgence.
    PURE-MIND: A Population-based Study of Covert Cerebrovascular Disease and Its Contribution to Age-Related Cognitive Decline
    Randomized trial comparing radical hysterectomy and pelvic node dissection vs simple hysterectomy and pelvic node dissection in patients with low risk cervical cancer defined as lesions measuring less than 2 cm with less than 50% stromal in
    Regulation and mechanism of action of transcription factor GATA4 in reproduction.
    Release, delivery and cell programming effects of platelet microparticles and microRNAs.
    Resynchronization/defibrillation for Ambulatory Heart Failure Trial in patients with Permanent AF (RAFT-PermAF)
    RNA Binding Protein Regulation of Cellular Migration and Adhesion During Cancer Cell Dissemination and Metastases Formation.
    Role of autotaxin bound to platelet-derived microparticles to development of vascular damage in arthritis.
    Role of developing hippocampus in organizing prefrontal cortical functions.
    Role of NOD-like receptors in lung immune response against respiratory virus infection
    Role of the innate immune system and evaluation of immunomodulatory strategies in herpes simplex virus encephalitis.
    Role or the autonomic nervous system and renin angiotensin system in chronic aortic valve regurgitation.
    Roles of exercise-induced gene, SPARC, against sarcopenia: Link between extracellular matrix and mitochondria.
    RUNX2-related Pulmonary Artery Remodeling and Calcification in Pulmonary Arterial Hypertension.
    Severe influenza in infants, children and youths : Role of clinical and epidemiologic risk factors
    Sex-specific regulation of food intake: the role of relaxin-3
    Signal integration and action potential coding in hippocampal microcircuits.
    STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury (STARRT-AKI).
    Substituted phenyl alkylureas as new potent antipsoriatic drugs: Mechanism of action and structure-activity relationships.
    Synaptic signaling and remodeling by CaM kinase II
    Targeted delivery into brain capillary endothelial cells for the treatment of Alzheimer disease
    Targeted Proteomics Analysis of the Adaptor Protein Grb2 Signaling Network Dynamics in Breast Cancer.
    The amyloid and beyond; A molecular answer to forget me not.
    The characterization of MICL, a novel negative regulator of the immune response in arthritis.
    The control of whisker motion in rodents.
    The critical role of human metapneumovirus fusion protein in the pathogenesis, treatment and prevention of childhood viral infections.
    The effect of an enhanced dietary portfolio flus exercise on cardiovascular risk in high risk individuals
    The molecular basis for the Warburg effect in pulmonary hypertension.
    Therapeutic nanobodies for amyotrophic lateral sclerosis.
    The reversibility of vasectomy used for contraception in men.
    The role of DEPTOR in the energy balance regulation.
    The role of different sub-population of adult-born neurons in the olfactory bulb network functioning and odor behavior.
    The role of TGF-beta in spinal cord damage and repair.
    The role of transcription factors Nur77 and retinoid X receptor (RXR) in the effect of antipsychotic drugs.
    The study of tobacco smoking and reward seeking using noninvasive brain stimulation and magnetic resonance imaging.
    Tranexamic acid during cystectomy trial (TACT)
    Transcriptional regulators of Leydig cell differentiation and function.
    Transfusion requirement in cardiac surgery III (TRICS III)
    Travail de nuit et difficultés de sommeil : déterminants psychosociaux et intervention psychologique.
    Understanding the behavioral and cerebral changes associated with pain empathy and its modulation in caregivers.
    Uniting traditional ways and science around medicinal plants/foods for the better prevention and management of Type 2 diabetes in Canadian First Nations
    Will mild vs. moderate physical activity suffice to abate the progression of subclinical atherosclerosis in sedentary adults?