Organisme : Instituts de recherche en santé du Canada

  Projets financés à l'Université Laval
    3alpha-hydroxysteroid dehydrogenase type 3 as a modulator of human adipose tissue function and distribution
    A comprehensive study of the natural history of ARSACS: An essential step towards clinical trial readiness and evidence-based interventions
    Addressing variation in practice in red blood cells transfusion for patients undergoing gastrointestinal cancer surgery
    Age-related patterns in the experience of chemotherapy-induced peripheral neuropathy
    Airway smooth muscle tone on asthmatic airway hyperresponsiveness
    Alberta oil sands development: impact on reproductive health
    Aldosterone antagonism and enhanced Clearance for Health Improvement EValuation in End-stage renal disease (ACHIEVE) Trial
    An analysis of the food environment in Canada: INFORMAS Canada
    A national study of opportunities and obstacles to successful community reintegration of forensic patients
    Anatomically relevant brachytherapy implants by a 3D printing and radiosenstizing approach
    Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA):A Randomized Controlled Trial
    An integrative brain health model for the individual prediction of cognitive decline
    A novel approach to treating inflammatory bowel diseases through the blocking of P2Y6 receptors
    Apixaban for the Reduction of Thrombo-Embolism in Patients with Device-Detected Sub-clinical Atrial Fibrillation
    A Pre-Clinical Research for Treatment of Prematurity and BronchoPulmonary Dysplasia through Intracrinology
    A randomized controlled effectiveness trial of urine CXCL10 chemokine monitoring post-renal transplant
    A Randomized Trial of Regional Radiotherapy in Luminal A Breast Cancer
    Arterial stiffness gradient as a new index of vascular aging: impact of blood pressure lowering medication
    Assessing the effectiveness of an approach based on the meanings of vocal behaviours in older people living with Alzheimer’s disease in long-term care facilities: DECIBELS Project
    Audit & Feedback Module Targeting Low-Value Clinical Practices in Injury Care: an Economic Evaluation
    A unique model to assess the oral transfer of dietary microRNAs
    Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): A Randomized Controlled Clinical Trial
    Biological sex, sex chromosomes and heart failure
    Biology of S100A8 and S100A9 proteins in Human Acute Myeloid Leukemia
    CD200 dysregulation in asthma: potential for therapy?
    Cellular mechanisms regulating the pathogenesis of secondary progressive CNS autoimmunity
    Characterization of HR-Killer1 and identification of small molecules for cancer therapy and enhanced gene editing using CRISPR/Cas9-based DNA repair strategies
    Chloride dysregulation and neuropathic pain: Linking molecular mechanisms with altered pain processing via identification of cellular and circuit level changes
    CLEAR trial: CoLchicinE in patients with Acute myocaRdial infarction
    Co-developing innovative approaches with Indigenous partners to foster coastal resilience, food security and sustainable marine harvests
    Comprehensive dissection of functional dependencies in a model protein network to reveal the mechanisms of robustness and fragility
    Control of metabolic inflammaging by traffic of B lymphocytes in adipose tissues
    CYCLE: An international, multi-centre, randomized clinical trial of early in-bed cycling for mechanically ventilated patients
    Deciphering the role of autophagy in neuronal migration and maturation
    Deciphering the role of DCIR in HIV-1 pathogenesis
    Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema
    Deciphering the role of the Yin Yang1 (YY1) transcription factor to understand pleuropulmonary blastoma
    DecreAsing sedentary behaviour and inCreasing physical acTIvity fOr healthy ageing (ACTION) study
    Defining the molecular basis of chemoradiation sensitivity in HPV+ head and neck cancers
    Defining the role of DEPTOR in the regulation of brown adipose tissue development/function and evaluation of its impact on systemic metabolism
    Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in chronic neurodegenerative diseases
    Derivation of a clinical decision rule for emergency department head CT scanning in seniors who have fallen
    Development and Usability Testing of HEARTPAIN: An Integrated Smartphone and Web-Based Intervention for Women with Cardiac Pain
    Development and validation of a cell-based assay to identify over-immunosuppression in kidney transplant recipients
    Differential effects of saturated and monounsaturated fatty acids on chylomicron secretion and the expression of key genes that regulate intestinal lipid metabolism in insulin-resistant subjects
    Ds institutions et des femmes: Évolution du nursing psychiatrique au Québec, 1912-1974
    Early Prediction of preeclampsia Using arteriaL Stiffness in high-risk prEgnancies; a multinational study (PULSE)
    E-GAMES Canada : la monétisation des jeux à l'ère des technologies mobiles et du numérique
    Elimination of cervical cancer through vaccination and screening in high HIV prevalence settings: a mathematical modeling and cost effectiveness study
    Elimination of senescent endothelial cells to prevent vascular dementia in aging atheroscierotic mice
    Elucidating the role of lipoprotein(a) in calcific aortic valve stenosis using novel proteomic and imaging approaches
    Elucidating the role of the Alzheimer risk factor CD2AP in brain capillary endothelial cells and vascular functions
    Elucidating the role of the IL-1 system in the pathogenesis of CNS autoimmunity
    Elucidation of bromodomain functions within SWI/SNF complexes
    Enabling monitoring of ultra-processed food consumption among Canadians: Development and validation of a screener
    Epidemiology and prognostic implications of panic disorder and generalised anxiety disorder in patients with coronary artery disease
    Estimating the effect size of rare genomic variants on cognitive and behavioral traits underlying neurodevelopmental disorders
    Estradiol receptor alpha mediates sex-specific responses in an animal model of sleep apnea
    État de la situation de l’hyperphagie boulimique au Québec : Connaissances, attitudes et ressources disponibles
    Étude de l'impact de l'innervation cutanée dans le Psoriasis
    Évaluation de l'implantation de l'accès adapté et de ses effets dans les groupes de médecine familiale universitaires
    Evaluation of a peer-led eHealth wheelchair skills training program: Training to Enhance Adaptation and Management for Wheelchair users (TEAM Wheel)
    Examining the consequences of child abuse on cerebral myelination
    Exploring the role of phosphoinositides in the trafficking of proteins to the apical complex in the malaria parasite Plasmodium falciparum
    Family-administered delirium detection in the critically ill
    Fathers Matter: A Prospective Study to Identify Determinants of Fathers' Engagement During Pregnancy
    Fatty acid metabolism in carriers of apolipoprotein E. epsilon 4 allele: determining the blood-to-brain link
    Finding the molecular drivers of calcific aortic valve stenosis
    From Birth to Adulthood: The Risk and Protective Factors Leading to Mental Health Problems (MHPs) in a Representative Population Sample.
    Fuchs endothelial corneal dystrophy and corneal transplantation: The traditional paradigm revisited
    Functional and clinical characterization of PALMD calcific aortic valve stenosis risk locus
    Functional dissection of the serotoninergic system in normal and pathological conditions
    Functional interaction between the androgen and the estrogen signalling pathways in prostate cancer
    Generalized anxiety disorder in older adults : Efficacy of a self-help treatment guided by trained lay providers
    Genetic analysis of spinothalamic neuron function in nociception
    Gestational exposure to chemicals related to hydraulic fracturing in Northeastern British Columbia, and their endocrine disrupting potential
    How does insulin interact with the blood-brain barrier? Therapeutic implications for diabetes and Alzheimer’s disease
    Human herpesvirus 6 and chromosomal integration
    Hydroxychloroquine in systemic lupus
    Identifying low bone turnover disease in chronic kidney disease in order to guide anti-fracture therapy
    Identifying the biological basis of GWAS hits for plasma triglyceride response to an omega-3 fatty acid supplementation
    Impacts of exercise and cognitive training interventions on neurocognitive functions in older adults with cardiovascular risk factors
    Implementation of a Stepped Care Cognitive-Behavioural Therapy for Insomnia in Routine Cancer Care
    Improving Corneal Endothelial Cell Adhesion
    Improving Corneal Endothelial Cell Adhesion
    Improving patient-centered depression care through the dissemination and implementation of the Depression Choice decision aid
    Inhibitory control of hippocampal inhibitory circuits: cell types, neuromodulation and function
    Integrative genomics and functional analyses to uncover the molecular mechanisms involved in bicuspid aortic valve disease
    Intercepting the "childhood risk syndrome" of schizophrenia and mood disorders along the developmental trajectory: A preclinical staging of children and adolescents at genetic risk
    Investigating the contribution of Shank3 in Alzheimer's disease
    Investigating the role of gating pore current in cardiac arrhythmias associated with dilated cardiomyopathy
    Investigating the Role of RECQL in Breast Cancer Susceptibility
    Investigation of the role of galectin-3 and its ligands in skeletal muscle strength, regeneration, and pathology
    Isoprostanes and phospholipases A2: Roles in the pathophysiology of preeclampsia
    La modulation des ganglions de la base par les afférences neurochimiques du tronc cérébral : implication dans la physiopathologie des troubles du mouvement
    Le lavage utérin au salin physiologique comme traitement de l'infertilité inexpliquée: un essai clinique randomisé à double insu
    Les maladies cardiométaboliques à l'ère de la révolution numérique
    Linking lifestyle behaviors, microbiota & cardiometabolic health from childhood to early adulthood: The QUALITY Cohort
    Manipulating the neuroimmune response to promote spinal cord repair
    Mapping anti-mitochondrial antibodies in systemic lupus erythematosus
    Mechanism of Ribosomal RNA Gene Silencing and Its Roles in Pluripotency and Cancer
    Mechanisms of neuronal and vascular impairments in ischemic retinopathies
    Mechanisms regulating contribution of pericytes to brain repair after stroke
    Mediterranean diet and physical activity: is the whole better than the sum of each part ? Clinical and mechanistic perspectives
    microRNA-132: from underlying mechanism of neurodegeneration to therapeutic application in Huntington’s disease
    Model-based impact evaluation of pre-exposure prophylaxis on HIV transmission among men who have sex with men in Montréal
    Molecular mechanisms of adipose tissue development
    Multifunctional properties of osteoprotegerin in muscular dystrophy and muscle repair
    Multi-pathway cholesterol depletion on top of FOLFIRINOX in newly diagnosed metastatic pancreatic adenocarcinoma: a feasibility and proof-of-concept study
    Muscarinic receptor antagonisrn as a novel mechanism for sensory nerve repair
    Neurophysiological biomarkers of insomnia treatment response: towards personalized therapeutic approaches in chronic insomnia
    Neurovascular adaptations driving stress-induced depression vs resilience
    New statistical methods for cohort studies of adverse effects of medications
    Nouvelles options thérapeutiques pour les patients atteints de psoriasis
    Novel therapeutic target for chronic stress-related channelopathy
    Omega-3 fatty acids in the prevention of breast cancer: role of obesity-related markers in breast tissues
    Optical nanoscopy of cytoskeletal and synaptic remodeling in neurons
    Orthologous CRISPR-Cas9 systems for genome editing: discovery, characterization and development for novel biotechnological applications
    Oxidative stress in the endoplasmic reticulum and its impact on liver inflammation in an aging mouse model
    PARP inhibition in PAH: A Phase 1 clinical trial
    Pathogenic Pathways and in-vitro modelization of Intracranial Aneurysms in populations of Inuit and French Canadian descent
    Pathogenic roles of platelets in sepsis
    Pharmacological Strategy to Prevent Ischemic Mitral Regurgitation: Preventing the Effects of Serotonin on Heart Valves.
    Pilot study of a community pharmacy-based program to enhance adherence to adjuvant endocrine therapy among breast
    Plasticity of midbrain nuclei after spinal cord injury
    Platelets and neutrophils: the two culprits mediating pain in inflammatory arthritis
    Poly(ADP-ribose) writers, readers, and erasers: Functions in DNA double-strand break repair and synthetic lethality
    Prebiotics to modify the gut microbiome and enhance immune checkpoint blockers
    Preclinical safety, pharmacokinetics, pharmacodynamics, and efficiency of microRNA oligonucleotides for Alzheimer's disease
    Predicting weight loss and metabolic improvements after bariatric surgery through a novel genetic and epigenetic score
    Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée
    Preventing pathological protein spread in Huntington's disease: relevance to pathology and treatment
    PROphylaxis for venous ThromboEmbolism in Severe Traumatic brain injury (PROTEST): a Double-blind Randomized Controlled trial
    Qanuikkat Siqinirmiut? A community-based study of southern Quebec Inuit health and wellbeing
    Quantifying Brown Adipose Tissue Thermogenesis in Obesity and Type 2 Diabetes
    Quantitative electroencephalography in rapid-eye-movement (REM) sleep: an early marker of cholinergic neurodegeneration in mild cognitive impairment
    Quantity of Opioids for Acute Pain and Limit Unused Medication (OPUM study)
    Real-World Evaluation of the Efficacy, Safety and Cost-Effectiveness of Statins for Primary Prevention of Cardiovascular Disease Among the Elderly – A Causal Perspective to Treatment Trajectory Analysis
    Regulation of chromosome cohesion and genome stability by a novel Histone modification
    Regulation of oncogenic receptor tyrosine kinase signalling networks by protein phosphorylation
    Removal of the GAA repeat with the CRISPR/Cas9 system in Friedreich patient cells and in the YG8sR mouse model
    Replication stress and pulmonary hypertension: Role for checkpoint kinase 1
    REVISE: Re-Evaluating the Inhibition of Stress Erosions in the ICU
    Rewiring the brain efficiently with cell transplantation in a pre-clinical model of Parkinson's disease
    Role of exosomes in cellular communication in asthma
    Role of the long non-coding RNA H19 as a novel biomarker and therapeutic target in right ventricular failure in pulmonary arterial hypertension
    Sex, hormones, and fertility: elucidating the molecular mechanism of action of transcription factor GATA4 in reproductive function
    Sex-specific investigations of Parkinson's disease mouse models: application for gonadal drugs repurposing
    Short, Medium, and Long Term Effectiveness of Interdisciplinary Teams and Other Primary Care Reforms in Ontario
    Signal integration and action potential coding in hippocampal microcircuits
    Situating Suicide Risk: An inquiry into the production of the lives and afterlives of neurobiological vulnerability
    Strengthening the implementation of "Health in all policies" at the county/municipal level in Ontario and Quebec using realist explanatory case studies and knowledge mobilization
    Stress and loss of ovarian function: novel insights into the origins and treatment of respiratory control disorders in females
    Stress Hydrocortisone in Pediatric Septic Shock (The SHIPSS trial)
    Stromal Gene Expression Predicts And May Drive Metastasis in Prostate Cancer
    Supporting the creation of a LEARNing INteGrated health system to mobilize context-adapted knowledge with a Wiki platform to Improve the transitions of frail Seniors from from hospitals and emergency Departments to the cOMmunity : The ...
    Suppression of regulatory B cells by neutrophils in a model of multiple sclerosis
    Surveillance of Complex Renal Cysts: The SOCRATIC study
    Systematic Prospective Assessment of Rapid Knowledge Synthesis - SPARKS Study
    The anti-oxidative DNA damage protein MTH1, the novel pulmonary hypertension Achilles heel
    The CART Canadian NP mifepristone implementation study
    The COMPAS+ project: Evaluating the impacts, implementation and scalability of a provincial quality improvement collaborative for the management of chronic diseases in primary care
    The Fit-for-Fertility Multicenter Randomized-Controlled Trial: Improving Reproductive, Maternal and Neonatal Outcomes in Women with Obesity and Infertility
    The IMPACT of food environment policies on the Canadian food supply, dietary intakes and health: evidence to inform policy action
    The impact of Monte Carlo dose calculations on prostate and breast low-dose rate brachytherapy dose-outcome relationships and radiobiological modeling
    The NeurO2 study: optimal brain oxygenation in neurocritically ill patients
    The physiology of adult neural stem cells
    The right care, for the right patient, at the right time, by the right provider: A value-based comparison of the management of ambulatory respiratory diseases in walk-in clinics, primary care physician practices and emergency departments
    The role of long non-coding RNAs in defining pluripotent stem cell states
    The transcriptional circuitry controlling the metabolic flexibility and host colonization under hypoxia in the human fungal pathogen Candida albicans
    Tissue Engineering of a functional Urethra for Autologous Reconstruction
    Towards a comprehensive model of Spindle Assembly Checkpoint silencing
    Trajectoires de soins et conditions propices aux soins ambulatoires
    Transformer les modèles actuels pour favoriser la sécurisation culturelle des soins offerts aux patients autochtones: Co-développement d'un nouveau modèle d’intervenant avec trois communautés atikamekw
    Understanding decision making in organ donation: a national study
    Understanding Head and Neck Squamous Cell Carcinoma onset in young adults
    Understanding the regulation and implication of Argonaute in microRNA-mediated gene silencing.
    Un nouveau vecteur de médicaments ophtalmiques à base de nanoparticules d'or
    Unravelling the role of primary cilia in the control of male fertility
    Untangling tau contribution to cognitive impairments in Huntington’s disease.
    Unveiling the role of alpha-synuclein clustering and Lewy body formation in Parkinson’s disease pathogenesis using an optogenetic-mediated protein aggregation system
    Vaccine Hesitancy and the Internet: An online ethnography in Canada
    Validation of Highly Potent Substituted Phenyl Alkylureas as Antipsoriatic Agents
    Vibrissa motion: motor strategies and facial expressions
    Vitamin D In the prevention of Viral-induced Asthma of preschoolers (DIVA): a multicentre randomized controlled trial
    Which exercise for chronic low back pain? Predicting response to exercise treatments for patients with low back pain
    Winning pathways toward accessibility: the case of dental services for people using wheelchairs