Fiche détaillée de la technologie

Titre de la technologie / Technology Title
    Résistance à la toxine diphtérique et à l'exotoxine A de Pseudomonas
Description / Description
    Diphtheria and Pseudomonas infections are very common worldwide. The toxins involved in the pathogenesis of those diseases act by inactivating the elongation factor-2 (EF-2), therefore blocking protein synthesis and leading to cell death. Diphthamide formation on EF-2 is a prerequisite step in the inactivation of EF-2, and Dph proteins have been identified as modulating this process. The present application concerns Dph2 deletion mutant genes and proteins and their uses in vitro and in vivo
Fiche descriptive / Fact sheet
    Inventeur / Inventor Collaborateur(s) / Collaborator(s)
    • Vincent Roy
    Contact / Contact Champs(s) d'intérêt(s) / Industry segment(s) Brevet(s) / Patent(s) Numéro de la technologie / File Number : 00705