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Titre de la technologie / Technology Title
A diagnostic tool to assess developmental competence in human oocytes or embryos
This non-invasive In Vitro Fertilization (IVF) test comprises a functional series of biomarkers used to assess the quality of human embryos before transplantation. Only the follicular cells (granulosa and cumulus) retrieved during oocyte collection, and usually discarded, are used. The diagnostic test is any sensitive RNA detection method used to analyze expression of mRNA or their expressed proteins in up to five biomarkers.
Markers have been screened from pooled eggs collected from 30 egg donors. From an initial screening of 125 biomarkers, 5 were found to be strong indicators of human oocyte probability to develop into fully developed individual.
- Mélanie Hamel
- Claude Robert